Synthetic substances that mimic marijuana, cocaine and other illegal drugs are making users across the nation seriously ill, causing seizures and hallucinations and even killing some people.

Struggling to avert a government shutdown, Republicans and Democrats each said Wednesday the other would be to blame if compromise talks on the budget fail to produce an agreement

HUNTSVILLE, Texas (AP) -- The U.S. Supreme Court blocked the first scheduled execution of a Texas death row inmate using pentobarbital on Tuesday.

The longest war in United States history puts an incredible strain on both military service members and their families. The mother in Florida who killed her two teenage children in January – whose husband had been deployed to the Middle East multiple times – suffered from depression and substance abuse issues. Cases of depression among military spouses is significantly higher than in the civilian population.

WASHINGTON (AP) -- House Speaker John Boehner said Tuesday that private talks with President Barack Obama failed to produce a deal to avoid a government shutdown

OAKLAND, Calif. (AP) -- A gunman testified Monday that he shot a California journalist three times in broad daylight on a downtown Oakland street to make sure he completed the killing ordered by the leader of a once-influential community group.

NEW YORK (AP) -- Manning Marable, an influential historian whose forthcoming Malcolm X biography could revise perceptions of the slain civil rights leader, died Friday, just days before the book described as his life's work was to be released. He was 60.

HOUSTON (AP) -- After their latest win on the road to an unlikely spot in the national title game, Connecticut's players talked about shocking the world. Butler's talked about unfinished business.

YUMA, Ariz. (AP) -- Three more Southwest Airlines jetliners have small, subsurface cracks that are similar to the cracks suspected of playing a role in the fuselage tear of a Boeing 737-300

WASHINGTON (AP) -- President Barack Obama formally launched his re-election campaign Monday, urging grass-roots supporters central to his first White House run to mobilize again to protect the change he's brought over the past two years.
The official start of his second White House bid, in the midst of three wars, a budget fight with Congress, and sluggish economic recovery, comes 20 months before the November 2012 election.